Esophageal cancer - fast facts
The Fred Hutch Cancer Center (Seattle, WA) concisely presents helpful information on causes, symptoms and treatment options for both types of esophageal cancer, as well as additional resources for patients.
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Metformin and reduced risk of esophageal squamous cell carcinoma
This population-based multinational case-control study across all five Nordic countries found that metformin use was associated with a substantially lower risk of esophageal squamous cell carcinoma (ESCC), with stronger protection seen at higher cumulative doses, supporting a dose-response relationship. Using high-quality national registry data from 13,
Survival after esophageal cancer diagnosis continues to improve
The U.S. National Cancer Institute recently released new data and analyses from the national SEER program of population-based cancer registries. They highlighted that there are now more than 18.6 million cancer survivors in the U.S. (as of 2023), and 5-year survival has reached 70%, reflecting
Coal smoke and risk of dying from esophageal and stomach cancer
While smoking and alcohol intake are the major causes of esophageal squamous cell carcinomas in most populations, exposure to environmental and occupational agents have been linked to increased risk in a number of settings (Etemadi, et al., JNCI 2024 Mar 7;116(3):379-388. doi: 10.1093/jnci/djad218.
Predicting risk of esophageal adenocarcinoma
This systematic review from investigators at the Karolinska Institute and Fujian Medical University evaluates nine risk prediction models from seven studies aimed at identifying individuals at high risk for esophageal adenocarcinoma (EAC) to improve targeted screening and early detection. The models commonly use predictors such as age, sex, GERD symptoms,