Latest research findings

May
10
Opportunities for esophageal cancer screening

Opportunities for esophageal cancer screening

Using the VA Central Cancer Registry, the authors investigated opportunites to undergo screening for esophageal adenocarcinoma (EAC), finding more than
1 min read
May
08
Indicators of prognosis among patients with esophageal adecnocarcinoma

Indicators of prognosis among patients with esophageal adecnocarcinoma

Dr. Matt Buas and colleagues analyzed clinical and lifestyle factors among 371 persons with esophageal adenocarcinoma. A number of factors
2 min read
May
07
Best practice guidelines for reducing use of PPIs

Best practice guidelines for reducing use of PPIs

Proton pump inhibitors (PPIs) are commonly used to treat  reflux, a key risk factor for esophageal adenocarcinoma. However, they have
3 min read
May
06
Prioritising BE surveillance using Cytsponge biomarker panel and clinical and epidemiologic risk factors

Prioritising BE surveillance using Cytsponge biomarker panel and clinical and epidemiologic risk factors

In addition to serving as a minimally invasive screening tool to help identify persons with Barrett's (BE), dysplasia and early
3 min read
May
04
Non-invasive capsule sponge with AI cytology shows promise for screening high-risk areas of China

Non-invasive capsule sponge with AI cytology shows promise for screening high-risk areas of China

Results from a study from a high-risk area in China indicate that esopphageal cells captured non-invasively via a capsule sponge, when combined with a trained artificial intelligence (AI) system can substantially reduce the need for endoscopy with histopathology, with a sensitivity of 93.7%.
2 min read
May
03
Evolution of esosphageal adenocarcinoma and implications for screening and surveillance

Evolution of esosphageal adenocarcinoma and implications for screening and surveillance

This nice review updates the molecular/genomic changes leading to esophageal adenocarcinoma and makes the link to more effective screening and treatment approaches.
1 min read
May
02
Asbestos exposure and increased risk of ESCC

Asbestos exposure and increased risk of ESCC

A meta-analysis of 34 studies of occupational exposure to asbestos reveals a 28% increased risk of esophageal squamous cell carcinoma, which increased to 84% among those most highly exposed.
1 min read
Apr
14
Importance of family history in Barrett's and esophageal adenocarcinoma

Importance of family history in Barrett's and esophageal adenocarcinoma

Family history of Barrett's and/or EAC was determined in 480 BE patients and 420 controls and validated using the Dutch nationwide histopathology database. A positive family history was found in 6.5% of BE patients, which is consistent with other studies, yielding a five-fold increased risk.
1 min read
Apr
13
Hormone therapy and esophageal adenocarcinoma

Hormone therapy and esophageal adenocarcinoma

Drs. Xie and colleagues observed a decreased risk of esophageal adenocarcinoma among women taking post-menopausal hormones in this population-based cohort study in Sweden with 693 EAC cases. This supports the concept that female sex hormones contribute to the lower incidence of EAC in women.
1 min read
Apr
12
Review of epidemiology of esophageal cancer and Barrett's

Review of epidemiology of esophageal cancer and Barrett's

This Review by Dr. Thrift at Baylor updates the trends in the incidence of esophageal cancer (both histologic types) and summarizes current knowledge of its risk factors.
1 min read